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The Ent ry class extendsPo rt, which in turn extends le tc le. ~ o ~ e ~ u e n t l y Se ab Entry objects can be added to aS e l e c t object in the same way as Channels and Ports. The c a l l method creates a channel object on which to receive the reply CallMs S, consisting a of message. It thenconstructsamessage,usingthe reference to this channel and a reference to the req object has queued this message send, it is suspended by a r ec e v e on the channel. i The server calls accept a tmessage the from entry. The accept method keeps a copy of the channel reference on which to reply in the local variable cm. The r e p l y method sends the reply message to this channel. Note that although s not the reply method performs as ~ c h r o n o usend operation, this does suspend the since must on channel. server the waitingreply client d a the Call, accept and r e p l y are not methods client since and server threads do not any sharevariable The c variable is only m accessed



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The contact element is a complex type of element because it contains other elements. If an element isn t de ned by giving it child elements, it s a simple type of element. To reference a schema in an XML document, refer to it like this:

var minText = <textarea name= Keywords onBlur= setMetaTag() + style= width:350;height:32 rows= 2 wrap= virtual ></textarea>

(mod 25)





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The Whitehall II study used as its target cohort all civil servants working in the London of ces of 20 Whitehall departments during 1985 8 The total sample size was just over 10 000 with a 2:1 male to female ratio The initial questionnaire and screening was carried out between 1985 and 1988 with regular and ongoing follow-ups The overall aim of this study was to investigate the biological mechanisms that might account for the social inequalities in cardiovascular disease and diabetes including the role of the traditional and established risk factors such as smoking, physical activity, blood pressure and cholesterol; dietary factors were subsequently included in the study (Further details of this study can be found at http://wwwuclacuk/whitehallII/Cohortpro lepdf.

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) Cross-sectional studies If one is using a risk marker or a symptom as the measure of outcome then it is possible to get immediate results using a survey of a cross-section of the population If one assessed diet and supplement usage in a large sample of people and then measured a disease risk marker or symptom one could look for correlations between consumption of a particular substance and the measured outcome Thus in a dietary context one could look at the relationship between measured saturated fat intake and blood cholesterol concentration or between habitual salt intake and blood pressure In 8 it is suggested that in cross-sectional studies in populations with high average soy intakes (but not in low soy populations), women with the highest intakes of soy have the highest bone mineral density.

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This has been used to support the case that phyto-oestrogens in soy products or supplements may protect against osteoporosis Limitations of observational studies Observational studies can never prove a hypothesis although in some cases the cumulative weight of evidence from such studies may well be accepted as such proof The problem of confounding variables affects the validity of all such observational studies For example, a negative correlation between fruit and vegetable intake and age-speci c cancer rates in different countries does not necessarily mean that fruit and vegetables protect against cancer There may be numerous important differences between the populations in the study and these other differences may account for the apparent protective effect of fruit and vegetables.

9

Time trends may show that changes in fruit and vegetable consumption have been associated with changes in age-speci c cancer rates but other dietary, lifestyle and environmental changes will also almost certainly have occurred over the same time period so is this association really an indication of cause and effect Whilst a large cohort study may show that those with high fruit and vegetable intake have a lower risk of developing cancer this does not prove a protective effect of fruit and vegetables High fruit and vegetable consumers are likely to be different from low consumers in other respects A confounding variable is one that is independently linked to both the suspected cause and the disease or other outcome Take the proposition that high alcohol consumption causes lung cancer If it was found in a case control or cohort study that high alcohol.

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