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Capaldi, K.P., Ferguson, S.J. and Radford, S.E. (1999) The greek key protein Apo-pseudoazurin folds through an obligate onpathway intermediate. J. Mol. Biol., 286, 1621 32. An interesting example of the use of CD in protein folding investigations. Eriksson, S., Kim, S.K., Kubista, M. and Norden, B. (1993) Binding of 4 ,6-diamidino-2-phenylindole (DAPI) to AT regions of DNA: evidence for an allosteric conformational change. Biochemistry, 32, 2987 98. An example of the application of LD to a study of ligand binding to DNA. Hanson, K.R. (1966) Applications of the sequence rule. I. Naming the paired ligands g, g at a tetrahedral atom Xggij. II. Naming the two faces of a trigonal atom Yghi. Journal of the American Chemical Society, 88, 2731 48. A description of the RS convention for enantiomers. Johnson, C.R., Morin, P.E., Arrowsmith, C.H. and Freire, E. (1995) Thermodynamic analysis of the structural stability of the tetrameric oligomerization domain of p53 tumor suppressor. Biochemistry, 34, 5309 16. A good example of the application of CD to investigations of protein structure. Kelly, S.M., Jess, T.J. and Price, N.C. (2005) How to study proteins by circular dichroism. Biochimica et Biophysica Acta, 1751, 119 39. A review of the application of CD to the study of proteins. Martin, S.R. and Schilstra, M.J. (2008) Circular dichroism and its application to the study of biomolecules, in Methods in Cell Biology, Vol. 84 (eds J.J. Correia and H.W. Detrich), pp. 263 93. A review of CD. Rodgers, A. and Norden, B. (1997) Circular Dichroism and Linear DIchroism, Oxford University Press. An excellent introduction to the theory and practice of CD and LD.



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where X is defined in Equation 7.106, px is the amplitude function, and N is the number of photon emissions per turn: (8.38)

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It is often assumed that hue can be speci ed by the wavelength of a monochromatic light. Unfortunately, this is not the case as illustrated by phenomena such as the Bezold Br cke hue shift. This hue shift occurs when one observes the hue of a monochromatic stimulus while changing its luminance. The hue will not remain constant. Some typical experimental results on the Bezold Br cke hue shift have been reported by Purdy (1931). Figure 6.5 represents some of the results from the Purdy (1931) research. The data in Figure 6.5 indicate the change in wavelength required to preserve a constant hue appearance across a reduction in luminance by a factor of 10. For example, to match the hue of 650 nm light at a given luminance would require a light of 620 nm at onetenth the luminance level ( 30 nm shift). Recall that a given monochromatic light will have the same relative tristimulus values no matter what the luminance level (since absolute luminance level is usually not considered in tristimulus colorimetry). Thus, tristimulus values alone would predict that the color of a monochromatic light should remain constant at all luminance levels. Purdy s results clearly disprove that hypothesis and point to the

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75 CHARACTERIZATION OF MATERIALS USED FOR SBS COMPRESSORS Generally, the same nonlinear materials are used for laser pulse compression as are used for conventional SBS Early experiments on pulse compression were conducted mainly using pressurized gases as the SBS media for SBS pulse compression of relatively long laser pulses (20- to 30-ns duration) Among them, argon and methane proved the most suitable for SBS compression due to their short phonon lifetime Sulfur hexa uoride was found to have the advantage of high Brillouin gain even at relatively low operational pressures, as well as high resistance to optical breakdown Table 71 lists some characteristics of pressurized gases used in Brillouin pulse compressors Nonlinear liquids offer better opportunities for SBS pulse compression than do pressurized gases due to their higher SBS gain and generally shorter phonon lifetime.

Some nonlinear liquids, used for SBS PC and pulse compression, are listed in Table 72 One of the key requirements for successful operation of a pulse compressor is the purity of the SBS medium used An SBS mirror can effectively block the focal region from the powerful pump, and ideally only near-SBS-threshold energy leaks through the mirror into the focal waist during the buildup of refraction index grating As a result, light intensity anywhere in the interaction volume does not reach the breakdown threshold even for an extremely powerful pump Since optical breakdown dramatically depends upon the concentration of microparticles in the focal area, it is necessary to purify the material to the highest possible degree Liquid uorocarbons are a class of nonlinear materials used for SBS pulse compression that are most resistant to optical breakdown For liquids of that class (eg.

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