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which it is exposed are numerous and diverse29 The translation of such insults, which include different pathogens and contact-sensitizing antigens, into cutaneous inflammation requires a complex interaction among multiple inflammatory mediators Notably, NF- B-mediated inflammation appears to be the final common pathway for the translation of environmental insults into inflammation of the skin NF- B, a powerful cellular signaling pathway, can be activated by IL-1, TNF- ,30 and as mentioned earlier, BK26 Interestingly, the epidermis is a storehouse of IL-1 and can produce considerable amounts of IL-1 and TNF- 31,32 It is known that ultraviolet (UV) radiation from sunlight induces activation of IL-1 and TNF- ,33 leading to NF- B-mediated inflammation NF- B regulates many genes in skin cells; however, those that are essential to the initiation of cutaneous inflammation include genes for E-selectin, cytokines, defensins (antibacterial peptides), and cell adhesion molecules30 Of special importance for cutaneous immunity is a subgroup of memory T cells with the ability to circulate preferentially to the skin These memory T cells are identified by a marker known as cutaneous lymphocyte antigen (CLA),34 and are generated in the lymph nodes that drain the skin Then, they are specifically recruited back to the skin during inflammation These unique skin-associated lymphocytes may be positive for either CD4 or CD8, and once activated, may be able to produce either type 1 T-cell cytokines (ie, INF- , IL-2, and lymphotoxin) or type 2 T-cell cytokines (ie, IL-4, IL-5, IL-10 and IL-13)29 It is the activation of the T cells and the subsequent release of cytokines and other effector molecules that result in clinically apparent T-cell-mediated inflammatory skin diseases29



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PS (7) > $host.ui.rawui.readkey() g VirtualKeyCode Character ControlKeyState ---------------------- --------------71 g 0

This returns information about the key code and other attributes of the key press instead of simply the character. The other way to access the host interfaces is through the Read-Host and Write-Host cmdlets. These cmdlets do approximately the same thing as the host methods, but can be a bit easier to use. In particular, the Read-Host cmdlet allows you to specify a prompt when reading:





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w = iz = i ( x + iy) = y + ix So we have the relations u = y v=x Hence y = x + 2 u = v + 2 That is, the line is transformed to v = u 2 This linear transformation maps one line into another one, as illustrated in Fig 92 EXAMPLE 92 Consider the transformation w = (1 + i ) z on the rectangular region shown in Fig 93 SOLUTION Notice that 1+ i 1+ i = 2 = 2 (cos /4 + i sin /4) = 2 ei / 4 2

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It even inserts a colon after your text when prompting. Using the features described in this section, you can instrument your scripts in order to debug their behavior. While this is a tried and true way of debugging, PowerShell provides some tools that are a bit more, shall we say, modern It's worth it to take a look at these features. 9.3.2 The Set-PSDebug cmdlet PowerShell provides some built-in debugging capabilities. These are available through the Set-PSDebug cmdlet. This cmdlet allows you to turn on tracing and stepping, and also enable a form of strict-mode . The syntax for this command is shown in figure 9.3. The details of each of these features are covered in the following sections. Tracing statement execution Basic script tracing is turned on by setting as follows:

[-Trace <Int 32>]

This tells us that the transformation will stretch lengths by 2 and rotate points in a counterclockwise direction about the origin by the angle /4 The transformed points are w = (1 + i ) z = (1 + i )( x + iy) = x y + i ( x + y) u= x y v=x+y So the points on the rectangle are transformed according to (1, 0) (1, i ) (1, i ) (0, 2i ) (0, i ) ( 1, i ) (0, 0) (0, 0) The transformed rectangle is illustrated in Fig 94

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