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FIGURE 35-1 Eicosanoids are signaling molecules made by oxygenation of essential fatty acids This gure shows the structure of several types of eicosanoids

Great hello PowerShell! But if we don t supply an argument:

z 2

we get a very impersonal greeting. So let s fix this up and change the script again. This time we ll take advantage of a here-string to generate a longer script.

PS >> >> >> >> (11) > @' if ($args) { $name = "$args" } else { $name = "world" } "Hello $name!" '@ > hello.ps1



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Hence, zlim ( z + 5) /(z + 2) = 2

This script has two lines. The first sets a local variable $name to the value of $args if it s defined. If it s not defined then it sets $name to world . If we run the script with no arguments, we get:

.

PS (12) > ./hello Hello world!

the generic greeting. If we run it with an argument, we get a specific greeting:

A function f ( z ) is continuous at a point z = a if the following three conditions are satis ed: lim f ( z ) exists z a f (a) exists lim f ( z ) = f (a) z a





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These are the same basic things we did with functions, and, as was the case with functions, they have limitations. It would be much more useful to have named, typed parameters as we did with functions. We could do the same multivariable assignment trick again, but we really want actual language support for formal argument to scripts. There s a problem, though. The formal arguments to a function are defined

outside the body of the function. This isn t possible to do with scripts since there s no declaration . The way we get around this is to introduce a new keyword in the PowerShell language param which we cover in the next section, 7.6.2 The param statement As mentioned in the previous section, if we want to specify formal parameters for a script, we need a new keyword to do this. This is the purpose of the param statement. Note that the param statement must be the first executable line in the script. Only comments and empty lines may precede it. Let s visit our hello example one more time. Again we ll use a here-string and redirection to create the script.

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FIGURE 35-2 The arachidonic acid cascade that leads to in ammation the host response to injury Although a large number of cytokines are found within sites of inflammation, two of these cytokines, namely, interleukin-1 (IL-1) and tumor necrosis factor(TNF- ), play a key role in orchestrating the mechanisms responsible for inflammation These two cytokines induce the production of lipid mediators, proteases, and free radicals, all of which play a direct role in the development of the deleterious effects of inflammation8 In fact, certain cytokines, including interferon- (INF- ) and granulocyte colonystimulating factor (G-CSF), amplify the inflammatory response by increasing the production of IL-1 and TNF- by macrophages8 other stimuli including complement components C3a and C5a, which will be briefly explained later in this chapter Other mast cell stimulators that promote the release of histamine include physical stimuli (eg, heat, cold, and sunlight), macrophagederived cytokines, bacterial toxins, venoms, trauma, and the presence of allergens Mast cells are also present in chronic inflammatory reactions, and may produce cytokines that contribute to fibrosis14,15 When a mast cell armed with IgE antibodies is reexposed to the specific allergen, a series of reactions takes place, leading eventually to the release of various potent mediators responsible for the clinical expression of immediate inflammatory-hypersensitivity reactions In the first step of this sequence, antigens bind to the IgE antibodies previously attached to the mast cells The bridging of IgE molecules with the underlying IgE-Fc receptors activates signal transduction pathways that will translate into three outcomes16: (1) degranulation, with the secretion of preformed mediators-like vasoactive amines (eg, histamine), neutral proteases (eg, chymase, tryptase, hydrolase), and proteoglycans (eg, heparin, chondroitin sulfate); (2) de novo synthesis of proinflammatory lipid mediators (ie, LTs C4, D4, and B4, and PG D2); and finally (3) synthesis and secretion of cytokines (ie, TNF- , IL-1, IL-3, IL-4, IL-5, IL-6, and GM-CSF), as well as chemokines, such as macrophage inflammatory protein (MIP)-1 and MIP-1 13.

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