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dermal component will be less visible when observed under a Wood s light40 In other words, if the lesions are more pronounced with Wood s light examination, there is a better chance for clinical improvement However, the Wood s light examination did not help to predict the clinical response to peels in a study by Lawrence41 The investigators felt that this occurred because there was such a high number of patients with a mixed epidermal/dermal form of melasma However, the consensus remains that patients in whom epidermal melasma predominates may respond better than those with a large dermal component Therefore, the Wood s examination is still a useful adjunct to determine a patient s prognosis in the treatment of melasma



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We could use the same approach regular expressions in PowerShell, which looks like:

or we could simply use the insert method on the string object to accomplish the same thing, but much more directly:

i i = exp(i ln i ) = exp i i + 2n = exp + 2n 2 2 where n = 0, 1, 2,, demonstrating that this is a multivalued function in fact it has in nitely many values Interestingly, they are all real numbers Consider n = 0 for which i i = exp( /2) = 481

While both examples require specific knowledge, using the Insert() method is more intuitive than using the regular expressions.





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If you can figure out Perl, PowerShell should be a breeze. There are, however, a couple things Perl programmers need to be aware of. The first two also apply to most other programming languages as well: Functions in PowerShell are invoked like commands. The result of a statement is not voided by default. These two items are discussed more in the section on C# and in chapter 7 on functions and scripts. There are a couple things that are very Perl-specific, however. Where Perl uses different sigils for different types of variables ($ for scalar, @ for array, and % for hashtables), PowerShell uses only the dollar sign for all types of variables. In fact, because it s based on .NET, PowerShell has to deal with many more data types than Perl does, so it s not possible to use sigils for each type. Another significant difference for Perl users is that arrays are passed to functions by reference automatically. If you have a variable containing three objects and you pass it to a function, it will be passed as a single argument containing a reference to the array. Let s look at an example to illustrate this. First we ll define a function that takes three arguments:

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The therapeutic objective is to retard the proliferation of melanocytes, inhibit the formation of melanosomes, and, further, promote the degradation of melanosomes42 Treatment options will be discussed in detail in 33, but must include a good high-SPF sunscreen with UVA protection and sun avoidance (Box 13-1) The sunscreen must be worn 24 hours a day Sun avoidance, UVA screens for car and home windows, and protective clothing, such as hats, are a great addition to a topical treatment regimen Topical treatments may include hydroquinone 2% to 4%, low-potency steroids, kojic acid, arbutin, azelaic acid, hydroxy acids, and retinoids Topical tretinoin improves epidermal hyperpigmentation by decreasing tyrosinase activity and melanin production as well as enhancing the desquamation of the epidermis43 Although tretinoin 01% has been studied as a single agent in the treatment of melasma,44,45 the time to improvement is lengthy (10 months, in one study) Therefore, most physicians use a combination of topical products The Kligman formula is a mixture consisting of 01% tretinoin, 50% hydroquinone, 01% dexamethasone, and hydrophilic ointment46 It has been a very popular melasma treatment since its introduction in 1975; however, this formula is currently not commercially available and must be formulated by a pharmacy A prescription combination preparation similar to the Kligman formula that contains hydroquinone 4%, tretinoin 005%, and fluocinolone 001% has been approved by the FDA and is a popular treatment for melasma Most prescription formulas contain 4% hydroquinone; however,

In Chap 3, we have already studied derivatives in detail In this section, we list some derivatives of the elementary functions for reference Given a polynomial f ( z ) = a0 + a1z + a2 z 2 + + an z n

PS (3) > function foo ($a,$b,$c) { "a=$a`nb=$b`nc=$c" }

Each argument is printed as expected. Now let s define an array containing 1,2,3 and pass that array to the function:

The derivative of the exponential function ez is d z e = ez dz (450)

This time, the three values all end up in $a because the array is passed by reference as a single argument instead of the elements being distributed across the arguments. Finally a common question that Perl users ask is if PowerShell has the equivalent of the Perl map operation. The answer is yes approximately. The ForeachObject cmdlet (or its alias %) is essentially the equivalent of Perl s map. The Perl map operation looks like:

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