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sleep patterns relative to drug therapy, but these changes are fairly durable over time Combined Psychological and Pharmacological Treatments Only ve studies have directly evaluated the combined or differential effects of behavioral and drug treatment modalities Three of those studies compared triazolam to relaxation (McClusky, Milby, Switzer, Williams, & Wooten, 1991; Milby et al, 1993) or sleep hygiene (Hauri, 1997), one compared estazolam with and without relaxation (Rosen, Lewin, Goldberg, & Woolfolk, 2000), and the other one (Morin, Colecchi, Stone, Sood, & Brink, 1999) compared cognitivebehavior therapy to temazepam Collectively, these studies indicate that both treatment modalities are effective in the short term Drug therapy produces quicker and slightly better results in the acute phase ( rst week) of treatment, whereas behavioral and drug therapies are equally effective in the short-term interval (4 to 8 weeks).



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NET Core? ASP.NET Core provides many improvements over the ASP.NET MVC​/Web API. Firstly, it is now one framework and not two. I really like it because it ...

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Clinical Microbiology Review 13:559 570 European Commission Regulation (EC) No 50/2000 of 10 January 2000 on the labelling of foodstuffs and food ingredients containing additives and avourings that have been genetically modi ed or have been produced from genetically modi ed organisms 2000 Of cial Journal of the European Union L 6:15 European Commission Regulation (EC) No 1830/2003 of the European Parliament and of the Council of 22 September 2003 concerning the traceability and labelling of genetically modi ed organisms and the traceability of food and feed products produced from genetically modi ed organisms and amending Directive 2001/18/EC 2003a Of cial Journal of the European Union L 268:24 European Commission Regulation (EC) No 1829/2003 of the European Parliament and of the Council of 22 September 2003 on genetically modi ed food and feed 2003b Of cial Journal of the European Commission L 268:1 Fantozzi, A, M Ermolli, M.

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Combined interventions appear to have a slight advantage over a single treatment modality during the initial course of treatment Furthermore, long-term effects have been fairly consistent for the single treatment modalities but more equivocal for the combined approach For instance, sleep improvements are well sustained after behavioral treatment while those obtained with hypnotic drugs are quickly lost after discontinuation of the medication Combined biobehavioral interventions may yield a slightly better outcome during initial treatment, but long-term effects are more equivocal Studies with short-term follow-ups ( 1 month) indicate that a combined intervention (ie, triazolam plus relaxation) produces more sustained bene ts than drug therapy alone (McClusky et al, 1991; Milby et al, 1993).

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Marini, B Balla, M Querci, and G Van den Eede 2008 Food Analysis and Methods 1:10 17 Feriotto, G, S Gardenghi, N Bianchi, and R Gambari 2003 Journal of Agricultural Food Chemistry 51:4640 4646 Flavell, R B, E Dart, R L Fuchs, and R T Fraley 1992 Biotechnology 10:141 144 Frewer, L, J Lassen, B Kettlitz, J Scholderer, V Beekman, and K G Berdal 2004 Food Chemistry and Toxicology 42:1181 1193 F rster, T 1948 Ann Phys 6:55 75 Garcia-Canas, V, R Gonzalez, and A Cifuentes 2002 Journal of Agricultural Food Chemistry 50:4497 4502 Germini, A, S Rossi, A Zanetti, R Corradini, C Fogher, and R Marchelli 2005 Journal of Agricultural Food Chemistry 53:3958 3962 Glynou, K, P C Ioannou, and T K Christopoulos 2004 Annals of Bioanalytical Chemistry 378: 1748 1753..

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The only two investigations with follow-ups exceeding six months in duration report more variable long-term outcomes among patients receiving a combined intervention relative to those treated with behavioral treatment alone (Hauri, 1997; Morin et al, 1999) Some of these patients retained their initial improvements whereas others returned to their baseline values Combined biobehavioral treatments should theoretically optimize outcome by capitalizing on the more immediate and potent effects of drug therapy and the more sustained effects of psychological interventions In practice, however, the limited evidence is not clear as to whether a combined intervention has an additive or subtractive effect on long-term outcome (Kendall & Lipman, 1991; Morin, 1996) In light of the mediating role of psychological factors in chronic insomnia, behavioral and attitudinal changes may be essential to sustain improvements in sleep patterns When combining behavioral and drug therapies, patients attributions of the.

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