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Such ndings have led researchers to suspect that a single major, but as yet unidenti ed, recessive gene accounts for a signi cant proportion of the variance in body mass (Bouchard, Perusse, Rice, & Rao, 1998) In addition, researchers also believe that body-fat distribution, resting metabolic rate, and weight gain in response to overconsumption are each controlled by genetic factors that may interact to predispose certain individuals to obesity (Chagnon et al, 2000; Feitosa et al, 2000; Levin, 2000) Among the rst genetic defects linked to obesity was the discovery of the ob gene and its protein product leptin (Zhang et al, 1994) Leptin, a hormone produced by fat cells, in uences hypothalamic regulation of energy intake and expenditure Laboratory mice that fail to produce leptin due to a genetic defect become obese as the result of excess energy intake and physical inactivity (Zhang et al. To move the Stage view: 1 Anantha Chandrakasan et al Design considerations for distributed microsensor systems In Proceedings of the IEEE Custom Integrated Circuits Conference, pages 279 286, May 1999 2 Hubert Zimmermann OSI reference model the ISO model of architecture for open systems interconnection IEEE Transactions on Communications, COM-28(4):425 432, April 1980 3 Ajay Chandra V Gummalla and John O Limb Wireless medium-access control protocols IEEE Communications Surveys, 3(2):2 15, 2000 4 C Siva Ram Murthy and B S Manoj 6 in Ad Hoc Wireless Networks Architectures and Protocols Prentice Hall, 2004 5 Dimitri Bertsekas and Robert Gallager Data Networks, Second Edition Prentice Hall, 1992 6 Henry Petroski To Engineer Is Human: The Role of Failure in Successful Design, pages 35 39 St Martin s Press, 1985 7 Woo Chool Park et al Trade-off energy and delay between MAC protocols for wireless sensor networks. , 1994) Moreover, the administration of recombinant leptin in such animals decreases food intake, increases physical activity, and reduces. asp.net mvc pdf editorC# ASP.NET PDF Editor Control: create, view, annotate, redact, edit ...
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