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Thus, there are three separate, redundant mechanisms regulating renin secretion (neural signals, afferent arteriolar pressure, and NaCl at the macula densa). This redundancy reflects the importance of the RAS and angiotensin II, in particular, in regulating blood pressure. Among the most significant actions of circulating angiotensin II produced by the global RAS is general arteriolar vasoconstriction. This vasoconstriction acts in parallel with sympathetically mediated neural control. This raises total peripheral resistance, thereby increasing blood pressure. The importance of this system makes the RAS a natural target for pharmacological intervention to reduce high blood pressure. A number of blood pressure lowering pharmacological agents are aimed at components of the RAS, including ACE inhibitors and blockers of the arteriolar smooth muscle receptors for angiotensin II. Figures 7 4 to 7 7 illustrate the various features of the RAS described in the text and show how the system responds to a major fall in blood pressure resulting from a hemorrhage. Besides these primary mechanisms, angiotensin II acts in a negative feedback manner to inhibit renin production by acting directly on granular cells (by interacting with AT1 receptors on granular cells to increase intracellular Ca concentration, which inhibits renin production). Most of the time it is appropriate for the vasoconstrictive and sodium retaining actions of angiotensin II to be exerted in parallel. However, by having both a global and an intrarenal RAS, it is possible to separate these actions, such that changes in sodium excretion can be effected without, at the same time, altering vascular resistance elsewhere in the body.



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From this markup, it should be clear that so long as you name and place your controllers, actions, and views correctly, there isn t really very much work for you to do. The framework will automatically locate and execute files for you, using its default routes, without requiring any manual intervention. As you proceed through this chapter and the remainder of this book, you ll learn a little more about how these standard Zend Framework conventions can be used to your advantage, by reducing the amount of manual coding required in getting an application up and running.

The partial derivative of T with respect to xkg is Fkg Z9 Z9 Tp = Z9 Fkg Z9 xkg Z9 Z9 Fkg where Z9 is a 1 9 vector of zeros and





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In addition, these polysaccharides can be hydrolyzed, catalytically or enzymatically, to produce sugars, a valuable fermentation feedstock for the production of ethanol, citric acid, lactic acid, and dibasic acids such as succinic acid Vegetable oils are obtained from seed oil plants such as palm, sunflower, and soya The predominant source of vegetable oils in many countries is rapeseed oil Vegetable oils are a major feedstock for the oleochemical industry (surfactants, dispersants, and personal care products) and are now successfully entering new markets such as diesel fuel, lubricants, polyurethane monomers, functional polymer additives and solvents Plant fibers (lignocellulosic fibers) are extracted from plants such as hemp and flax, and can replace cotton and polyester fibers in textile materials and glass fibers in insulation products.

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The two previous case studies involved human-to-human communication and have showed that improving the communication flow between mobile users and their non-mobile counterparts can deliver strong business benefits when enabled with wireless data applications. Another value chain that can be improved through the application of wireless data is the sharing of information from machines in the field, such as vending machines (inventory control and product freshness monitoring), vehicles (truck driver performance or passenger car repair information that can be sensed by a central repair site), or appliances (remote diagnostic tests). Technology advancements in devices such as appliances and cars have placed microprocessors, memory, and other computer pieces directly into these machines. Machine designers are becoming aware that they can use the information gathered by these embedded computers to improve machine performance or to avoid machine repairs. Typically, this is done by storing performance data of the machine and using remote diagnostic tools and/or human experts to analyze the data to predict and avoid machine failures or to send tuning parameters to the machines. The range of applications is growing and is a natural area for future growth given the richness of digital data now captured and available in machines. A truck can easily report its vital statistics (engine speed,

to the second paragraph that sets the font property and the size property, as shown in boldface here:

Specialty products such as highly complex bioactive molecules, the synthesis of which is often beyond the ability and economics of laboratories, and a wide range of chemicals are currently extracted from plants for a wide range of markets, from crude herbal remedies to very high value pharmaceutical intermediates Fats and greases, the proper categorization may be debatable since those are by-products of the reduction of animal biomass into component parts However, most fats and greases, and some oils, are not available for bioenergy use until after they become a.

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